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. 2022 Aug 18;16(8):e0010724. doi: 10.1371/journal.pntd.0010724

Table 1. Demographics and clinical features of the study cohort.

*Within the ARI cohort, the specific viral etiology was known in 29 patients. The percentage reported is out of a total of 29 patients. Of these 29 patients, 4 patients tested positive for two different viruses concurrently on multiplex PCR–influenza and adenovirus (n = 1), influenza and human coronavirus OC43 (n = 1), parainfluenza and respiratory syncytial virus (n = 1), and parainfluenza and enterovirus virus (n = 1). **Any one of fatigue, somnolence, headache, concentration impairment or memory impairment.

Dengue Cohort (n = 48) ARI Cohort (n = 161) p-value
Demographics
Age
    Median (range), years 37.0 (21–68) 34.0 (22–79) 0.39
Male sex, no. (%) 30 (62.5) 46 (28.6) <0.001
Ethnicity, no. (%) 0.21
    Chinese 29 (60.4) 77 (47.8)
    Malay 12 (25.0) 36 (22.4)
    Indian 3 (6.3) 21 (13.0)
    Others 4 (33.3) 27 (16.8)
Co-morbidities, no. (%)
    Diabetes mellitus 2 (4.2) 5 (3.1) 0.72
    Hypertension 4 (8.3) 16 (9.9) 0.74
    Ischemic heart disease 2 (4.2) 2 (1.2) 0.19
Disposition
Hospitalised, no (%) 37 (77.1) 29 (18.0) <0.001
Study Compliance
Completed at least 3 months of study follow-up, no (%) 39 (81.3) 158 (98.1) <0.001
Viral Etiology
Severe dengue, no. (%) 1 (2.0) - NA
Respiratory virus type, no. (%)*
Influenza A & B - 14 (48.3)
Rhinovirus - 6 (20.7)
Adenovirus - 4 (13.8)
Human coronavirus (OC43) - 4 (13.8)
Parainfluenza - 3 (10.3)
Human coronavirus (NL63) - 1 (3.4)
Enterovirus - 1 (3.4)
Clinical Features
Symptom type at presentation, no (%)
Any symptom** 46 (95.8) 152 (94.4) 1.00
Fatigue 38 (79.2) 136 (84.5) 0.51
Somnolence 32 (66.7) 93 (57.8) 0.32
Headache 29 (60.4) 119 (74.0) 0.07
Concentration impairment 29 (60.4) 95 (59.0) 0.86
Memory impairment 13 (27.1) 28 (17.4) 0.15