Skip to main content
. Author manuscript; available in PMC: 2023 Sep 1.
Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2022 Aug 5;1870(9):140831. doi: 10.1016/j.bbapap.2022.140831

Figure 4. Effect of the P1 residue on the inhibition of CTRB1, CTRB2, bCTRA, and CTRB1 mutants D236R and S242T by phage display-selected SGPI-2 variants.

Figure 4.

A set of five inhibitor variants (CT1-CT5) were used that differ only at their P1 residue as indicated in the inset. KD values for each enzyme were determined after 3 h and 27 h incubation and the lower values corresponding to tighter binding were plotted.