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. 2022 Aug 29;11(1):550–561. doi: 10.1080/21623945.2022.2115212

Figure 3.

Figure 3.

Screening for post-BS-related markers by a comprehensive strategy. (a) The lasso regression analysis identified 12 genes with minimum lambda values and non-zero parameters. (b) SVM-RFE used the minimum RMSE to identify 28 genes. (c) Intersection of LASSO, SVM-RFE, and magento modules for DEGs. (d) Differential expression of STMN2, SFRP4, APOE and MXRA5 in the combined dataset (e) Validation of STMN2, SFRP4, APOE and MXRA5 expression in GSE53376. Student’s t-test was used to compare between the two groups. *P < 0.05; **P < 0.01. BS, bariatric surgery; SVM-RFE, support vector machine-recursive feature elimination; RMSE, root mean square error; DEGs, differentially expressed genes.