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. 2022 Aug 29;11(1):550–561. doi: 10.1080/21623945.2022.2115212

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Assessing the role of immunomodulation in bariatric surgery. (a) GSEA analysis of the effect on immune pathways after bariatric surgery. (b) xCell analysis results to observe the altered level of immune cell infiltration after surgery. (c, d, e) Correlation of SFRP4, APOE and MXRA5 expression levels and the degree of immune cell infiltration. Student’s t-test was used to compare between the two groups. *P < 0.05; **P < 0.01. Spearman correlation analysis was performed to calculate correlation coefficients. GSEA, Gene set enrichment analysis.