Table 4.

Medication adherence across included studies evaluating pharmacist-driven interventions

Study	Adherence Measurement	Timing of Measurement	Results (Intervention versus Control)
Ho 2014	Percent of patients with a PDC >80% based on prescription claims data	1 yr	Statin: 93.2% vs 71.3%, p<0.001 ACEI/ARB: 93.1% vs 81.7%, p =0.03 Clopidogrel: 86.8% vs 70.7%, p=0.03 Beta-blocker: 88.1% vs 84.8%, p= 0.59 Overall (Cardiac Medications): 89.3% vs 73.9%, p=0.003
Calvert 2012	Percent of patients with a PDC >75% based on prescription claims data	6 mo	Beta-blocker: 71% vs 49%, p=0.03 Statin: 58% vs 49%, p=0.34 Overall (Statin/Beta-blocker): 53% vs 38%, p=0.11
Calvert 2012	Percent of patients reporting taking medications as prescribed	6 mo	Aspirin: 100% vs 100%, p=NR Beta-blocker: 90% vs 96%, p=0.50 Statin: 98% vs 98%, p=0.99 Overall (Aspirin/Statin/Beta-blocker): 91% vs 94%, p=0.50
Calvert 2012	Median score on a 4-item Morisky Adherence Scale using a 5-item Likert scale	6 mo	19 vs 19, P = 0.40
Ma 2010	Mean (SD) Continuous multiple-intervala	1 yr	Statin: 0.88 (0.3) vs 0.9 (0.3), p=0.51 Beta-blocker: 0.97 (1.1) vs 0.91 (0.4), p=0.56 ACEI: 1.02 (0.8) vs 0.93 (0.3), p=0.25
Faulkner 2000	Average proportion of doses taken based on pill count	6 wk	Statin: 92% vs 89%, p>0.05
Faulkner 2000	Average proportion of doses taken based on pill count	12 wk	Statin: 88% vs 86%, p>0.05
Faulkner 2000	Percent of patients filling 80% or more of their prescriptions based on prescription refill records	1 yr	Statin: 67% vs 33%, p <0.05

^aRatio of days’ supply obtained to total days between refill records

ACEI= Angiotensin-converting-enzyme inhibitors; PDC=proportion of days covered; SD=standard deviation