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Hepatitis B Virologic and Clinical Reactivation
| Baseline HBV DNA | |||
|---|---|---|---|
| <LLOQ n = 37 |
≥LLOQ n = 74 |
Overall N = 111 |
|
| HBV virologic reactivation (increase to ≥LLOQ or >1 log10 IU/ML increase) | 33 (89) | 48 (65) | 81 (73) |
| Clinical reactivation (HBV reactivation + ALT> 2 × ULN)a | 3 (8) | 7 (10) | 10 (9) |
ALT, alanine aminotransferase; HBV, hepatitis B virus; LLOQ, lower limit of quantification; ULN, upper limit of normal.
ULN, 34 IU/mL for women and 43 IU/mL for men.
