Table 2.
Demographics and Baseline Characteristics of Patients With and Without Hepatitis B Virologic Reactivation
| Hepatitis B Reactivation | ||
|---|---|---|
| Yes (n = 81) |
No (n = 30) |
|
| Mean (range) age, y | 55 (36–76) | 55 (32–70) |
| Male, n (%) | 30 (37) | 12 (40) |
| Mean (range) BMI, kg/m2 | 25 (17–34) | 24 (19–34) |
| Cirrhosis, n (%) | 14 (17) | 4 (13) |
| Mean (range) ALT, U/L | 73 (17–228) | 54 (17–281) |
| HCV | ||
| Genotype 1, n (%) | 52 (64) | 16 (53) |
| Genotype 2, n (%) | 29 (36) | 14 (47) |
| Mean (range) HCV RNA, log10 IU/mL | 5.8 (4.2–7.1) | 6.0 (3.8–6.9) |
| HCV treatment experienced, n (%) | 30 (37) | 7 (23) |
| IL-28B CC, n (%) | 59 (73) | 26 (87) |
| HBV | ||
| Genotype B, n (%) | 58 (85) | 21 (87) |
| Genotype C, n (%) | 9 (13) | 3 (13) |
| Mean (range) HBV DNA, log10 IU/mL | 1.9 (1.3–5.5) | 2.5 (1.3–5.8) |
| HBV DNA <LLOQ, n (%) | 33 (41) | 4 (13) |
| HBsAg positive, n (%) | 80 (99) | 30 (100) |
| Mean (range) HBsAg, IU/mL | 554 (0–5435) | 646 (0.1–6777) |
| HBeAg positive, n (%) | 1 (1) | 0 |
| HBV treatment experienced, n (%) | 5 (6) | 0 |
ALT, alanine aminotransferase; BMI, body mass index; HBeAg, hepatitis B e antigen; HBsAg, hepatitis B s antigen; HBV, hepatitis B virus; HCV, hepatitis C virus; LLOQ, lower limit of quantification.