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Silencing circKIF4A suppresses glucose metabolism and prevents breast cancer cells from metastasis. (a) Transfection with si-circKIF4A reduced glucose uptake. (b) A reduction in lactate production was observed when circKIF4A was silenced. (c) The ability of BC cells transfected with siRNAs to migrate and invade was measured using transwell migration (scale bar = 100 μm), respectively. ∗P < 0.05; ∗∗P < 0.01.
