Table 2.
The association between the risk of GA and the genetic polymorphisms.
| SNP | WT Ho/ Ht/ VR Ho | Codominant model | Dominant model | Recessive model | VR allele vs. WT allele | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| VR Ho vs. WT Ho | Ht vs. WT Ho | |||||||||||||||
| Control | GA | C_HWE | P | OR (95% CI) | P | OR (95% CI) | AIC | P | OR (95% CI) | AIC | P | OR (95% CI) | AIC | P | OR (95% CI) | |
| rs10754558(CC/CG/GG) | 132/266/109 | 100/158/56 | 0.29 | 0.064 | 0.68 (0.45-1.03) | 0.14 | 0.78 (0.57-1.09) | 1094.6 | 0.074 | 0.75 (0.55-1.03) | 1093.1 | 0.2 | 0.79 (0.55-1.13) | 1094.7 | 0.056 | 0.82 (0.67-1.01) |
| rs35829419(CC/CA/AA) | 503/4/0 | 313/1/0 | 1 | 0.38 | 0.40 (0.04-3.61) | 1095.6 | ||||||||||
| rs3738448(GG/GT/TT) | 325/165/17 | 204/98/11 | 0.57 | 0.94 | 1.03 (0.47-2.25) | 0.72 | 0.95 (0.70-1.28) | 1096.3 | 0.75 | 0.95 (0.71-1.28) | 1094.3 | 0.9 | 1.05 (0.49-2.27) | 1094.4 | 0.82 | 0.97 (0.75-1.25) |
| rs3806268(AA/AG/GG) | 124/265/117 | 98/136/75 | 0.33 | 0.3 | 0.81 (0.55-1.20) | 0.012 | 0.65 (0.46-0.91) | 1081.3 | 0.026 | 0.70 (0.51-0.96) | 1080.8 | 0.71 | 1.07 (0.76-1.49) | 1085.6 | 0.24 | 0.89 (0.73-1.08) |
| rs7525979(CC/CT/TT) | 325/165/17 | 211/92/11 | 0.57 | 0.99 | 1.00 (0.46-2.17) | 0.33 | 0.86 (0.63-1.17) | 1097.4 | 0.36 | 0.87 (0.65-1.17) | 1095.5 | 0.91 | 1.05 (0.48-2.26) | 1096.3 | 0.46 | 0.91 (0.70-1.17) |
OR: odds ratio; VR: variant; WT: wild-type; Ht: heterozygote; VR Ho: variant homozygote; WT Ho: wide-type homozygote.