Table 3.
Resistance-susceptibility profiles of ExPEC strains to antimicrobials of avian or human use in Brazil.
| Antimicrobial class | Antimicrobials | Disc content (μg) | Use: avian (A) human (H) |
Resistance breakpoint (mm) | Healthy carcasse |
Diseased carcasse |
Overall Resistance %b | Resistant strains | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| S %a | I % | R % | S % | I % | R % | |||||||
| Penicillin | Ampicillin | 10 | A/H | ≤13 | 11.2 | 5,5 | 83.3 | 11.3 | 11 | 77.7 | 81.5 | 44A, 15C, 48B, 36A, 43A, 5B, 21C, 42C, 35, 31C, 52B, 55B, 5A, 24A, 54B, 6 60A, 38B, 37B, 3 39B, 46, 41A, 2 2B |
| Aminoglycoside | Amikacin | 30 | A/H | ≤14 | 72.4 | 11 | 16.6 | 100 | 0 | 0 | 1,1 | 36A, 42B, 2B |
| Gentamicin | 10 | A/H | ≤12 | 61.3 | 11 | 27.7 | 56.6 | 0 | 44.4 | 33.3 | 32, 48B, 52B, 55B, 42B, 54B, 37B, 41A, 2B |
|
| Streptomycin | 10 | H | ≤11 | 0 | 0 | 100 | 0 | 0 | 100 | 100 | 4A, 48A, 32, 44A, 15C, 30C, 48B, 36A, 43A, 5B, 21C, 42C, 35, 31C, 52B, 55B, 5A, 42B, 24A, 54B, 60A, 38B, 37B, 39B, 46, 41A, 2B |
|
| Fluoroquinolone | Ciprofloxacin | 5 | A/H | ≤15 | 22.3 | 27.7 | 50 | 67.7 | 0 | 33.3 | 44.4 | 30C, 43A, 35, 42B, 24A, 60A, 38B, 37B, 39B, 46, 41A, 2B |
| Levofloxacin | 5 | H | ≤13 | 27.9 | 11 | 61.1 | 55.6 | 11.1 | 33.3 | 51.8 | 15C, 30C, 43A, 42C, 35, 5A, 42B, 24A, 60A, 38B, 37B, 46, 41A, 2B |
|
| Phenicol | Chloramphenicol | 30 | A/H | ≤12 | 66.8 | 5,5 | 27.7 | 88.9 | 11.1 | 0 | 18.5 | 37B, 39B, 46, 41A, 2B |
| Cephalosporin | Ceftazidim | 30 | H | ≤14 | 56.7 | 27.7 | 16.6 | 66.7 | 22.2 | 11.1 | 14.8 | 54B, 39B, 46, 41A |
| Cefalotin | 30 | H | ≤14 | 5,7 | 5,5 | 88.8 | 0 | 11.1 | 88.9 | 88.8 | 32, 44A, 15C, 30C, 48B, 36A, 43A, 5B, 21C, 42C, 31C, 52B, 55B, 5A, 42B, 24A, 54B, 60A, 38B, 37B, 39B, 46, 41A, 2B |
|
| Carbapenem | Imipenem | 10 | H | ≤13 | 100 | 0 | 0 | 100 | 0 | 0 | 0 | - |
| Tetracycline | Tetracycline | 30 | A/H | ≤14 | 0 | 0 | 100 | 0 | 0 | 100 | 100 | 4A, 48A, 32, 44A, 15C, 30C, 48B, 36A, 43A, 5B, 21C, 42C, 35, 31C, 52B, 55B, 5A, 42B, 24A, 54B, 60A, 38B, 37B, 39B, 46, 41A, 2B |
| Monobactam | Aztreonam | 30 | H | ≤15 | 33.8 | 22.2 | 44 | 44.5 | 44.4 | 11.1 | 33.3 | 5B, 21C, 31C, 5A, 54B, 38B, 9B, 46, 41A, 2B |
| Beta-lactam/beta-lactamase inhibitor | Amoxycillin/clavulanic acid | 20/10 | H | ≤13 | 22.3 | 5,5 | 72.2 | 33.4 | 0 | 66.6 | 70.4 | 44A, 36A, 5B, 21C, 42C, 35, 31C, 52B, 55B, 5A, 24A, 54B, 60A, 38B, 37B, 39B, 46, 41A, 2B |
a
Percentage of E. coli strains sensitive (S), intermediary sensitive (I) or resistant (R) out of the total of isolates.
b
The overall resistance rate is given by the number of non-susceptible isolates divided by the total number of isolates submitted to antibiogram tests.