Table 1.
Demographic, clinical and ART characteristics for 214 pregnant women included in this study from HGNI and HFSE, Rio de Janeiro, Brazil.
| Variable | ARTexp women (n = 36, 16.8%) | ARTn women (n = 178, 83.2%) |
|---|---|---|
| Age (years), Median (IQR) | 30.7 (26.8–34.8) | 27.6 (23.3–31.9) |
| Race, n (%) | ||
| White | 16 (44.4) | 58 (32.5) |
| Non-white | 20 (55.6) | 113 (63.5) |
| Not declared | – | 7 (4.0) |
| Previous pregnancies, n (%) | ||
| 1–2 | 16 (44.4) | 91 (51.1) |
| ≥3 | 12 (33.3) | 62 (34.8) |
| Living children, n (%)a | ||
| 1–2 | 13 (36.1) | 95 (53.4) |
| >3 | 9 (25.0) | 40 (22.5) |
| HIV exposure category, n (%) | ||
| Sexual | 31 (88.1) | 166 (93.8) |
| Intravenous drug use | 0 (0.0) | 2 (1.1) |
| Unknown | 5 (11.9) | 10 (5.1) |
| Previous AIDS-defining illness, n (%) | 5 (13.9) | 1 (0.6) |
| Time until HIV diagnosis (months), median (IQR) | 36 (21.2–55.5) | 7.3 (1.2–19.3) |
| CD4 (cells/mm3) data | ||
| Nadir ≥ 200 cells/μL, n (%) | 22 (61.1) | 159 (89.3) |
| Baseline, median (IQR) | 351.5 (193.8–466.0) | 422.5 (297.8–569.8) |
| Higher value during pregnancy, median (IQR) | 446.0 (288.0–561.0) | 520.0 (379.0–681.0) |
| Lower value during pregnancy, median (IQR) | 338.0 (190.5–342.9) | 404.0 (292.0–551.0) |
| Viral load (copies/mL) | ||
| Baseline, median (IQR) | 400.0 (400.0–2900.0) | 4950.0 (640.0–29000.0) |
| Viral load > 1000 copies/mL during pregnancy, n (%) | 10 (28.6) | 28 (17.9) |
| Gestational age on baseline, mean (±SE) | 15.7 (1.0) | 21.1 (0.6) |
| Route of delivery, n (%) | ||
| Vaginal route | 16 (44.4) | 61 (34.3) |
| Cesarean section | 20 (55.6) | 117 (65.7) |
| Pregnancy outcome, n (%) | ||
| Term birth | 30 (83.4) | 163 (91.5) |
| Preterm birth | 4 (11.1) | 14 (7.8) |
| Abortion | 2 (5.5) | 1 (0.7) |
| ART-based regimen, n (%) | ||
| NNRTI | 16 (44.4) | 73 (41.1) |
| PI | 19 (52.8) | 103 (57.8) |
| PI + NNRTI | 1 (2.8) | – |
| NRTI | – | 2 (1.1) |
| ART use during pregnancy (weeks), median (IQR) | N/A | 16.1 (10.0–22.0) |
| ARV modification, n (%) | 24 (66.7%) | 10 (5.6) |
aExcluding current pregnancy; IQR = interquartile range; SE = standard error.