Table 3.
ADR, intensity, causality with ARV, evolution, duration and outcome in 178 ARTn women from HGNI and HFSE, Rio de Janeiro, Brazil.
| Variable | Gastrintestinal (n = 29) | Cutaneous (n = 11) | Hematologic (n = 4) | Hepatic (n = 3) |
|---|---|---|---|---|
| Intensity | ||||
| Mild | 26 (89.6) | 4 (36.4) | 2 (50.0) | 2 (66.7) |
| Moderate | 2 (6.9) | 5 (45.5) | 2 (50.0) | 1 (33.3) |
| Severe | 1 (3.5) | 2 (18.2) | 0 (0.0) | 0 (0.0) |
| Causality | ||||
| Definitely ARV-related | 18 (62.1) | 5 (45.5) | 1 (25.0) | 1 (33.3) |
| Probably ARV-related | 6 (20.7) | 6 (54.5) | 3 (75.0) | 2 (66.7) |
| Possibly ARV-related | 5 (17.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| Seriousness | 0 (0.0) | 0 (0.0) | 1 (25.0) | 0 (0.0) |
| Drug discontinuation | 2 (6.9) | 7 (63.6) | 1 (25.0) | 1 (33.3) |
| Outcome | ||||
| Resolved | 13 (44.8) | 11 (100.0) | 1 (25.0) | 1 (33.3) |
| Ongoing | 16 (55.2) | 0 (0.0) | 3 (75.0) | 2 (66.7) |
| Type of ART | ||||
| NNRTI | 1 (3.5) | 10 (90.9) | 2 (50.0) | 2 (66.7) |
| PI | 28 (96.5) | 1 (9.1) | 2 (50.0) | 1 (33.3) |
| Time to ADR onset (weeks), median (IQR) | 0.3 (0.0–0.7) | 0.5 (0.3–0.8) | 2.1 (1.1–3.2) | 0.6 (0.6–0.8) |
| ADR duration (weeks), median (IQR) | 2.1 (1.4–3.6) | 0.6 (0.2–0.7) | 1.3 (0.7–2.9) | 5.4 (3.1–5.7) |
IQR = interquartile range.