Fig. 2.

Renal amyloidosis in a patient with visceral leishmaniasis and HIV. (A) Abundant mesangial amyloid deposits (black arrowhead; enlarged in (B)) and interstitial fibrosis (white asterisk); FAOG stain; 100×, (B) almost complete obliteration of the glomerular architecture by mesangial amyloid deposits; FAOG stain; 600×, (C) amyloid deposits in arteriolar wall that are congophilic and produce apple-green birefringence; Congo red; 600×, (D) typical ultrastructural appearance of amyloid fibrils in the mesangium; transmission electron microscopy (uranyl acetate and lead citrate), and (E) amyloid fibrils are also seen in capillary membranes in a subendothelial location; transmission electron microscopy (uranyl acetate and lead citrate).

Reprinted from de Vallière, et al., The American Journal of Tropical Medicine and Hygiene 81(2):209–12. Copyright (2009) with permission from The American Journal of Tropical Medicine and Hygiene.³⁵