Table 1.
MiRNAs involved in EV71infection.
| miRNAs | Function | Target | Ref. |
|---|---|---|---|
| miR-296-5p | Repression of viral replication | EV71 VP3 and VP1-coding region | 37 |
| miR-23b | Repression of viral replication | EV71 3′ UTR | 38 |
| miR373 and miR542-5p | Repression of viral replication | EV71 5′ UTR | 39 |
| miRNA-548 | Enhancement of replication of EV71 and VSV | IFN-λ1 | 41 |
| miR-146a | Enhancement of viral pathogenesis | IRAK1 and TRAF6 | 42 |
| miR-526a | Repression of viral replication | CYLD | 43 |
| miR-146a and miR-370 | Enhancement of EV71-induced cell apoptosis | SOS1and GADD45β | 44 |
| miR-141 | Enhancement of EV propagation | eIF4E | 45 |
| miR-27a | Repression of viral replication | EGFR | 46 |
| miR-1246 | Contribution to the neurological pathogenesis | DLG3 | 47 |