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. Author manuscript; available in PMC: 2023 Sep 1.
Published in final edited form as: J Thorac Oncol. 2022 Jun 24;17(9):1109–1121. doi: 10.1016/j.jtho.2022.06.004

Figure 6. POU2F3 expression in normal airways.

Figure 6.

Triple synaptophysin (brown chromogen), p40 (green chromogen), and POU2F3 (red chromogen) IHC in representative bronchiolar cross-sections shows nuclear POU2F3 expression in rare cells that are distinct from the flask-shaped synaptophysin-positive resident pulmonary neuroendocrine cells, with POU2F3-positive nuclei overlying a discretely separate continuous p40-positive basal cell layer and located at or above the level of ciliated cell nuclei.

Abbreviations: IHC immunohistochemistry, SYN synaptophysin