Table 2.
Univariable and multivariable Cox regression for predictors of post-transplant mortality
| Univariable analysis | Multivariable analysis | |||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-value | HR | 95% CI | p-value | |
| Age (year) | 1.02 | 0.97–1.06 | 0.46 | 1.01 | 0.97–1.06 | 0.59 |
| Sex (male) | 0.54 | 0.23–1.28 | 0.16 | 0.37 | 0.14–1.02 | 0.054 |
| Diabetes | 2.03 | 0.79–5.24 | 0.14 | 0.98 | 0.31–3.09 | 0.97 |
| Hepatic encephalopathy | 2.66 | 0.90–7.92 | 0.08 | 1.97 | 0.59–6.58 | 0.27 |
| Hepatocellular carcinoma | 1.64 | 0.55–4.88 | 0.37 | 2.27 | 0.55–9.38 | 0.26 |
| MELD-Na (per 1 point) | 1.04 | 0.99–1.10 | 0.11 | 1.06 | 0.99–1.13 | 0.08 |
| Body composition | ||||||
| Non-sarcopenic & non-visceral obese | Ref | - | - | Ref | - | - |
| Non-sarcopenic & visceral obese | 0.47 | 0.09–2.32 | 0.35 | 0.45 | 0.09–2.30 | 0.34 |
| Sarcopenic & non-visceral obese | 0.86 | 0.24–3.03 | 0.81 | 1.25 | 0.33–4.80 | 0.74 |
| Sarcopenic & visceral obese | 2.92 | 1.04–8.23 | 0.04 | 3.50 | 1.10–11.15 | 0.03 |
Abbreviations: AIH/PBC/PSC, autoimmune hepatitis/primary biliary cholangitis/primary sclerosing cholangitis; MELD-Na, model for end-stage liver disease-sodium; NAFLD/NASH, nonalcoholic fatty liver disease/nonalcoholic steatohepatitis