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. 2022 Aug 30;13:4970. doi: 10.1038/s41467-022-32323-y

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A Phylogenetic plot of top 20 most abundant microbial species in the nasopharyngeal airway of infants hospitalized for bronchiolitis. The colors in the inner circle annotate the six major phyla. The colors in the two internal rings represent the magnitude of the association between the relative abundance of each species and higher severity (PPV use and intensive care use) outcomes. Greyscale bars on the outside of the circular graph are proportional to the microbial species’ mean relative abundance. B The pirate plots show the comparison of the distribution of ten most abundant species in the nasopharyngeal microbiome in infants hospitalized for bronchiolitis, according to the PPV use. Each point represents each infant. The gray bar and rectangle represent the mean and 95% confidence interval. In the violin plots, the width represents the probability that infants take on a specific relative abundance. The between-group differences in the abundance were tested by fitting Poisson regression models. n = 244 biologically independent samples. Abbreviations: FC fold change, FDR false discovery rate, PPV positive pressure ventilation.