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. 2022 Aug 30;12:14795. doi: 10.1038/s41598-022-18913-2

Table 3.

The conversion (according to GC) of ketones 1, 3 and 5 to corresponding lactones in different DES medium.

mDES from Table1 Time days Conversion (%) Control reactionsa
Ketone 1 Lactone 2 Ketone 3 Lactone 4 Ketone 5 Lactone 6 Ketone 1,3,5 Lactone 2,4,6
7 1 59.8 40.1 73.2 26.8 88.6 11.4 100 0
2 11.1 88.9 9.9 90.1 47.6 52.4 100 0
3 1.0 99.0 0.9 99.1 7.9 92.1 100 0
6 0 100 0 100 0 100 100 0
8 1 26.0 74.0 41.7 58.3 68.1 31.9 100 0
2 2.0 98.0 8.7 91.3 15.8 84.2 100 0
3 1.9 98.1 5.0 95.0 9.3 90.7 100 0
6 1.3 98.7 4.7 95.3 7.0 93.0 100 0
9 1 25.7 74.3 65.1 34.9 60.2 39.8 100 0
2 18.3 81.7 36.0 64.0 31.4 68.6 100 0
3 16.5 83.5 22.8 77.2 29.1 70.9 100 0
6 12.1 87.9 19.1 80.9 28.0 72.0 100 0
10 1 97.4 2.6 95.4 4.5 95.0 5.0 100 0
2 94.0 6.0 94.9 5.1 95.8 4.2 100 0
3 94.0 6.0 92.5 7.5 95.5 4.5 100 0
6 76.4 23.6 91.9 8.1 94.4 5.6 100 0
11 1 10.7 89.3 35.2 64.8 49.1 50.9 100 0
2 9.4 90.6 16.2 83.8 33.8 66.2 100 0
3 6.8 93.2 14.6 85.4 29.4 70.6 100 0
6 3.6 96.4 7.4 92.6 21.3 78.7 100 0

aControl reactions were carried out by excluding respectively lipase, octanoic acid and oxidant from the reaction mixture.