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. 2017 Mar 7;21(3):255–262. doi: 10.1016/j.bjid.2016.12.008

Table 2.

Medications and comorbidities of the patients by group (n = 257).

Non-statin group (n = 167) Statin group (n = 90) p-Value
Comorbidities
COPD 46 (27.5) 28 (31.1) 0.547
Hypertension 110 (65.8) 70 (77.7) 0.047
Diabetes 49 (29.3) 37 (41.1) 0.056
Malignancy 33 (19.7) 15 (16.6) 0.544
Coronary artery disease 37 (22.1) 47 (52.2) <0.001
Cerebrovascular disease 32 (19.1) 23 (25.5) 0.233
Chronic renal failure 12 (7.1) 7 (7.7) 0.863
Chronic heart failure 21 (12.5) 17 (18.8) 0.174
Chronic liver disease 10 (5.9) 1 (1.1) 0.065
Peripheral vascular disease 6 (3.5) 6 (6.6) 0.265



Preadmission medication
ACE I or angiotensin II antagonists 28 (16.7) 24 (26.6) 0.059
Aspirin 30 (17.9) 30 (33.3) 0.005
Beta blockers 17 (10.1) 22 (24.4) 0.002
Calcium antagonists 43 (25.7) 34 (37.7) 0.045
Antiplatelet agents (other) 19 (11.3) 31 (34.4) <0.001
Spironolactone 20 (11.9) 9 (10.0) 0.633
Furosemide 17 (10.1) 9 (10.0) 0.964
Nitrate esters 23 (13.7) 22 (24.4) 0.032
Oral hypoglycemics 22 (13.1) 27 (30.0) 0.001
Digoxin 14 (8.3) 9 (10.0) 0.665
Trimetazidine 14 (8.3) 28 (31.1) <0.001
Antiarrhythmic agents 5 (2.9) 8 (8.8) 0.040
Insulin 9 (5.3) 8 (8.8) 0.282
Warfarin 5 (2.9) 2 (2.2) 0.717
Donepezil hydrochloride 8 (4.7) 4 (4.4) 0.900
Memantine 6 (3.5) 2 (2.2) 0.546
Steroid use for chronic diseases 3 (1.7) 3 (3.3) 0.436

Abbreviations: COPD, chronic obstructive pulmonary disease; ACEI, angiotensin-converting enzyme inhibitors.

Data are shown as n (%).