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. 2022 Aug 17;13:837680. doi: 10.3389/fphar.2022.837680

TABLE 2.

List of analytes significantly associated with the 2 years composite endpoint of FVC decline >10%, DLCO decline >15% or death.

Analyte Adj. Hazard Ratio Adj. p-Value Class
Diacylglyceride (16:0_16:1) 0.51 0.010 Diglycerides
Diacylglyceride (18:1_18:3) 1.73 0.041 Diglycerides
Octadecenoic acid 0.54 0.018 Fatty acids
Dehydroepiandrosterone sulfate 0.57 0.031 Hormones and related
Lysophosphatidylcholine a C18:0 0.48 0.006 Lysophosphatidylcholines
Lysophosphatidylcholine a C16:1 0.52 0.013 Lysophosphatidylcholines
Hypoxanthine 0.60 0.044 Nucleobases and related
Phosphatidylcholine ae C42:5 1.74 0.036 Phosphatidylcholines
Phosphatidylcholine ae C44:6 1.70 0.039 Phosphatidylcholines
Triacylglyceride (16:1_34:1) 0.50 0.007 Triglycerides
Triacylglyceride (16:1_32:0) 0.52 0.013 Triglycerides
Triacylglyceride (16:1_34:0) 0.57 0.028 Triglycerides
Triacylglyceride (16:1_34:3) 0.58 0.038 Triglycerides
Triacylglyceride (16:1_32:2) 0.59 0.038 Triglycerides
Triacylglyceride (17:1_34:1) 0.60 0.043 Triglycerides
Choline 0.51 0.010 Vitamins and cofactors