Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Diagnostic feature of hyperreactive malarious splenomegaly (HMS) – Fakunle criteria.
| Major criteria | Minor criteria |
|---|---|
| Splenomegaly > 10 cm | Hepatic sinusoidal lymphocytosis |
| IgM > 2SD of local mean | Hypersplenism |
| High titers of antimalarial antibodies | Lymphocytic proliferation |
| Clinical and immunological response to antimalarial drug | Normal cellular and humoral immune response to antigenic challenge excluding Plasmodium |
| Occurrence within families and tribes |
