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. 2019 Nov 4;23(6):381–387. doi: 10.1016/j.bjid.2019.09.003

Table 4.

Association of the studied genotypes and variables of the anti-tuberculosis drug- induced liver injury treatment in the samples of the patients under treatment of TB included in the study.

Variable OR (95% CI) p-value (<0.10)
CYP2E1 Variant 4.57 (0.75–27.6) 0.09*
NULL GSTM1 0.58 (0.06–5.58) 0.6
NULL GSTT1 4.57 (0.76–27.6) 0.09*
Use of illicit drugs 0.39 (0.06–2.36) 0.3

Every patient who had at least one variant allele, regardless of the region, due to low frequency, was considered a variant genotype of CYP2E1. A p-value < 0.10 was considered significant due to the reduced number of patients included in the study.