. 2022 Aug 17;14:905035. doi: 10.3389/fnagi.2022.905035

TABLE 4.

Comparison of the gray matter volume of hippocampal subregions.

	NC		SCD		F	interaction P-value	η²

	Normal BMI (n = 29)	High BMI (n = 17)	Normal BMI (n = 38)	High BMI (n = 27)
Fimbria^a	140.02 ± 27.68	136.88 ± 42.62	140.71 ± 42.62	135.30 ± 30.08	0.468	0.496	0.005
Hippocampal tail^a	1131.37 ± 148.57	1124.49 ± 145.31	1211.41 ± 145.31	1174.71 ± 150.21	4.077	0.046	0.040
Hippocampal fissure^a	311.08 ± 57.45	332.80 ± 43.91	313.00 ± 43.91	334.24 ± 61.54	0.085	0.771	0.001
Parasubiculum^a	118.63 ± 22.72	128.19 ± 39.14	125.66 ± 39.14	129.06 ± 26.69	0.565	0.454	0.006
HATA^a	372.18 ± 42.04	365.76 ± 61.01	385.50 ± 61.01	383.93 ± 47.42	0.356	0.552	0.004
Subiculum^a	875.96 ± 88.15	864.50 ± 108.60	900.03 ± 108.6	911.20 ± 99.37	0.002	0.961	0.000
Presubiculum^a	578.68 ± 61.11	587.29 ± 91.56	603.47 ± 91.56	599.56 ± 72.49	1.342	0.249	0.013
CA1^a,b	1261.17 ± 173.97	1191.34 ± 173.97	1229.23 ± 149.79	1319.61 ± 157.07	8.607	0.004	0.080
CA3^a	395.54 ± 58.86	390.07 ± 68.34	414.46 ± 56.01	433.96 ± 57.62	0.479	0.490	0.005
CA4^a	464.64 ± 52.40	459.88 ± 64.73	489.89 ± 48.30	502.93 ± 53.16	0.256	0.614	0.003
Molecular layer^a	1069.42 ± 112.25	1045.28 ± 149.39	1107.70 ± 117.61	1139.04 ± 124.48	6.309	0.014	0.060
GC-ML-DG^a	535.52 ± 62.95	524.13 ± 78.41	562.64 ± 60.00	576.00 ± 67.07	0.723	0.397	0.007

^aContinuous variable, two-way ANOVA is adopted, and mean ± SD is used for statistical description; the unit of volume is cubic millimeter.

^bThere is an interaction between population grouping and BMI grouping after correction by Bonferroni method.

HATA, hippocampal amygdala transition area; CA, cornu ammonis; GC-ML-DG, granule cell layer and molecular layer of the dentate gyrus. The two-way ANOVA was carried out with age, gender, years of education, hypertension, hyperlipidemia, type II diabetes mellitus, whole hippocampus volume, and intracranial volume as covariates.