Table 3.
Site in BCMA | Surface complementarity to hAPRIL | Distance to hAPRIL | Surface complementarity to hBAFF | Distance to hBAFF | ||||
---|---|---|---|---|---|---|---|---|
WT | Single mutant | WT | Single mutant | WT | Single mutant | WT | Single mutant | |
S16G | 0.65 | 0.51 | N/A | N/A | 0.76 | 0.76 | 3.2 Å (to Leu72) | 3.2 Å (to Leu72) |
H19Y | 0.88 | 0.21 | 3.8 Å (to Arg81) | 2.1 Å (to Arg81) | 0.88 | 0.2 | 3.7 Å (to Arg92) | 2.0 Å (to Arg92) |
T36A | 0.00 | 0.00 | N/A | N/A | N/A | N/A | N/A | N/A |
N/A, not applicable.