Table 3.

Correlations between PSEN1 and the Gene Markers of the Immune Subsets determined by TIMER2.0.

Cell Type	Colon Adenocarcinoma (COAD)
	Gene Marker	PSEN1 Correlation (TIMER 2.0)
		Purity-adjusted partial	P Value
		spearman's rho
T cell exhaustion	PD-1(PDCD1)	0.147	**
	CTLA4	0.228	***
	LAG3	0.189	***
	TIM-3 (HAVCR2)	0.35	***
Regulatory T cells	FOXP3	0.317	***
	TGFβ (TGFB1)	0.327	***
	IL-10	0.283	***
	PTGIR	0.163	**
	ITGA4	0.452	***
	STAT5B	0.328	***
CAFs	CD44	0.255	***
	α-SMA	0.215	***
	FAP	0.254	***
	FSP1 (S100A4)	0.141	**
	PDGFRα	0.394	***
	PDGFRβ	0.294	***

**P < 0.01, ***P < 0.001.