Figure 5.

H&E staining at PODs 1, 5, and 40. (A) At POD 1, a high number of PMNs (arrowhead) had infiltrated the bleb area. (B) Red blood cells around the implantation site were clearly visible (arrows). (C) Some vessel swelling was visible around the conjunctiva (arrows). (D) POD 5 revealed significant granulation tissue in the bleb with many fibroblasts (e.g., asterisks) and macrophages (e.g., arrowhead) present. Additionally, an increased thickness of the conjunctiva was noted at this time point (arrows). (E) At POD 40, fewer inflammatory cells resided in the bleb; however, a low number of macrophages and PMNs were sporadically observed. The bleb wall contracted, and granulation tissue was replaced. (F) Although minimal, some foreign body giant cells are visible around the SIBS microshunt (arrowheads). *Position of SIBS microshunt. All images were taken at 200× magnification.