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. 2022 Aug 17;9:927642. doi: 10.3389/fcvm.2022.927642

TABLE 2.

Secondary outcomes of the meta-analysis (continuous variables).

COP group TCC group
Radiation doses n Mean ± SD n Mean ± SD
Perez et al. (15) 41 1,747.7 ± 1,411.3 32 1,144.5 ± 671.3
Maier et al. (16) 127 4,919 ± 3,559 589 3,714 ± 3,168
Heterogeneity: χ2 = 0.35, df = 1 (p = 0.554), I2 = 0%.
Fixed-effects model, SMD: 0.394, 95% CI: (0.216, 0.572),
p < 0.001.
Fluoroscopic time n Mean ± SD n Mean ± SD
Pascual et al. (22) 161 26.4 ± 11.6 161 29.4 ± 14.8
Perez et al. (15) 41 27.0 ± 17.5 32 26.3 ± 9
Heterogeneity: χ2 = 1.10, df = 1 (p = 0.294), I2 = 9.3%. Fixed-effects model, SMD: −0.175, 95% CI: (−0.373, 0.023), p = 0.083.
Implantation depth n Mean ± SD n Mean ± SD
Pascual et al. (22) 161 5.3 ± 2.3 161 5.9 ± 2.5
Maier et al. (16) 127 3.9 ± 2.7 589 4.9 ± 2.6
Heterogeneity: χ2 = 0.79, df = 1 (p = 0.375), I2 = 0%. Fixed-effects model, SMD: −0.324, 95% CI: (−0.469, −0.180), p < 0.001.
Mean gradient n Mean ± SD n Mean ± SD
Pascual et al. (22) 161 7.0 ± 3.3 161 7.4 ± 3.4
Perez et al. (15) 41 2.8 ± 4.8 32 4.8 ± 6.7
Raza et al. (20) 46 6.7 ± 3.3 17 6.4 ± 2.6
Heterogeneity: χ2 = 1.50, df = 2 (p = 0.472), I2 = 0%. Fixed-effects model, SMD: −0.132, 95% CI: (−0.319, 0.054), p = 0.165.
Length of hospital stay n Mean ± SD n Mean ± SD
Pascual et al. (22) 161 5.1 ± 3.7 161 6.0 ± 3.0
Mendiz et al. (23) 156 2.9 ± 1.1 101 2.7 ± 1.1
Sadiq et al. (14) 75 2.5 ± 2.5 104 2.9 ± 2.3
Maier et al. (16) 127 7.7 ± 5.1 589 10.2 ± 6.4
Raza et al. (20) 46 4.7 ± 5.5 17 4.4 ± 3.6
Heterogeneity: χ2 = 14.42, df = 4 (p = 0.006), I2 = 72.3%. Random-effects model, SMD: −0.148, 95% CI: (−0.377, 0.082), p = 0.207.

COP, cusp-overlap projection; SD, standard difference; SMD, standard mean difference; TCC, three-cusp coplanar. A random-effects model was used if significant heterogeneity existed. Otherwise the fixed-effects model was used.