Table 3. Univariate and multivariate logistic regression analysis with COVID-19 vaccine uptake in children as the dependent variable (reference: COVID-19 vaccine denial).
|
Variable |
Unadjusted OR (95% CI) |
P-value |
Adjusted OR (95% CI)a |
P-value |
|---|---|---|---|---|
|
Gender (mothers vs. fathers) |
1.03 (0.69 – 1.54) |
0.89 |
NS |
|
|
Parents’ age (years) |
1.08 (1.05 – 1.10) |
<0.001 |
1.07 (1.04 – 1.10) |
<0.001 |
|
Marital status (singles/widowed/divorced vs. married) |
1.01 (0.64 – 1.59) |
0.97 |
NS |
|
|
Educational level (University degree vs. High school) |
1.91 (1.23 – 2.99) |
0.004 |
NS |
|
|
MSc/PhD degree (yes vs. no) |
1.35 (0.95 – 1.91) |
0.09 |
NS |
|
|
Self-perceived financial status |
|
|
NS |
|
|
Good/very good |
1.21 (0.69 – 2.09) |
0.50 |
|
|
|
Moderate |
0.87 (0.51 – 1.48) |
0.61 |
|
|
|
Very poor/poor |
1 (reference) |
|
|
|
|
Self-perceived health status |
|
|
NS |
|
|
Good/very good |
1.57 (0.63 – 3.91) |
0.34 |
|
|
|
Moderate |
1.32 (0.49 – 3.53) |
0.58 |
|
|
|
Very poor/poor |
1 (reference) |
|
|
|
|
Parents’ chronic disease (yes vs. no) |
1.08 (0.72 – 1.63) |
0.70 |
NS |
|
|
Previous parents’ COVID-19 diagnosis (no vs. yes) |
2.59 (1.26 – 5.35) |
0.01 |
NS |
|
|
Family/friends with COVID-19 disease (no vs. yes) |
1.29 (0.92 – 1.83) |
0.14 |
NS |
|
|
Living with elderly people or vulnerable groups during the COVID-19 pandemic (yes vs. no) |
1.28 (0.89 – 1.84) |
0.19 |
NS |
|
|
Parents’ COVID-19 vaccination uptake (yes vs. no) |
17.23 (5.39 – 55.01) |
<0.001 |
NS |
|
|
Parents’ seasonal influenza vaccination in 2020 (yes vs. no) |
1.58 (1.11 – 2.24) |
0.01 |
NS |
|
|
Self-perceived severity of COVID-19 |
1.42 (1.27 – 1.59) |
<0.001 |
NS |
|
|
Self-perceived knowledge regarding COVID-19 |
1.31 (1.12 – 1.52) |
0.001 |
NS |
|
|
Self-perceived knowledge regarding COVID-19 vaccines |
1.36 (1.19 – 1.55) |
<0.001 |
NS |
|
|
Concerns about the side effects of COVID-19 vaccination |
0.84 (0.79 – 0.89) |
<0.001 |
NS |
|
|
Trust in COVID-19 vaccines |
1.43 (1.29 – 1.57) |
<0.001 |
1.29 (1.15 – 1.44) |
<0.001 |
|
COVID-19 vaccination promotes public health |
1.55 (1.36 0 1.76) |
<0.001 |
NS |
|
|
Vaccination is beneficial |
1.93 (1.53 – 2.44) |
<0.001 |
1.42 (1.09 – 1.86) |
0.01 |
|
Trust in the government regarding the information about the COVID-19 vaccines |
1.18 (1.11 – 1.24) |
<0.001 |
NS |
|
|
Trust in scientists regarding the information about the COVID-19 vaccines |
1.28 (1.19 – 1.38) |
<0.001 |
NS |
|
|
Trust in family doctors regarding the information about the COVID-19 vaccines |
1.26 (1.14 – 1.40) |
<0.001 |
NS |
|
An odds ratio <1 indicates a negative association, while an odds ratio >1 indicates a positive association.
CI: confidence interval; NS: not selected by the backward elimination procedure in the multivariable logistic regression analysis with a significance level set at 0.05; OR: odds ratio
R2 for the final multivariate model was 27%