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Comparison of sNfL and sBDNF levels in grade 3 vs. grade 0–2 PIPN patients. Shown are the (A) sNfL levels, and (B) sBDNF levels for patients with grade 3 and grade 0–2 PIPN during and 6 months after paclitaxel treatment. Data are presented as mean ± standard error, and the sNfL comparison has been adjusted for patient age. sNfL, serum neurofilament light chain; sBDNF, serum brain-derived neurotrophic factor; PIPN, paclitaxel-induced peripheral neuropathy.
