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. 2022 Aug 17;16:896172. doi: 10.3389/fncel.2022.896172

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Copyright © 2022 Elsherbini, Ghoneim, El-Mancy, Ebrahim, El-Sherbiny, El-Shafey, Al-Serwi and Elsherbiny.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A–E) Microscopic pictures of immunostained cerebral cortical sections against Kir4.1 of control and treated groups. (A,B) Control group showing expression in astrocytes near the blood vessels (black arrows) and negative expression in neurons (short arrow). (C–E) Cerebral cortical sections from the TAA-treated group. (C) Micrograph showing vacuolation and pyknotic nuclei of astrocytes with decreased expression (white arrows). (D,E) Hypertrophied astrocytes with moderated expression (arrowhead). X: 400 bar 50 and X: 200 bar 100.