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. 2022 Aug 17;16:896172. doi: 10.3389/fncel.2022.896172

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Copyright © 2022 Elsherbini, Ghoneim, El-Mancy, Ebrahim, El-Sherbiny, El-Shafey, Al-Serwi and Elsherbiny.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A–D) Microscopic pictures of immunostained cerebral cortical sections against GFAP of control and treated groups. (A,B) Control group showing positively brown stained astrocytes (black arrows) with evident expression in their processes (arrowhead). (C,D) Cerebral cortical sections from the TAA-treated group showing hypertrophied astrocytes (white arrows) and processes (arrowhead). X: 400 bar 50 and X: 1000 bar 20. (E) Graph showing mean surface area of astrocytes. Values represent mean ± SD (^***p < 0.001 vs. control group).