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. 2022 Aug 17;12:966321. doi: 10.3389/fonc.2022.966321

Table 3.

Perioperative data.

Total Type of surgery p-value
n=95 RAMIE (n=71) MIE (n=24)
Characteristics of surgery
Length of surgery, minutes (median, [IQR])

395.0 [360.5-449.0]

395.0 [351.0-448.5]

399.5 [367.5-456.0]

0.6685
Blood loss, ml (median, [IQR]) 275 [] 250 [200-400] 400 [200-500] 0.1258
Blood transfusion 9 (9.9%) 5 (7.6%) 4 (17.4%) 0.2228
Anastomotic technique 0.0406
 Linear stapling 63 (66.3%) 44 (62.0%) 19 (79.2%)
 Circular stapling 32 (33.7%) 27 (38.0%) 5 (20.8%)
Length of stay, days
 ICU (median, [IQR]) 4 [3-9] 4 [3-6.5] 7 [4-18.5] 0.0280
 Total (median, [IQR]) 17 [11-28] 15 [11-25.5] 26 [13.8-61] 0.0012
Complications
 Any complication

56 (59.0%)

37 (52.1%)

19 (79.2%)

0.0198
Clavien Dindo 0.0188
 0 39 (41.1%) 34 (47.9%) 5 (20.8%)
 1 1 (1.1%) 0 (0.0%) 1 (4.2%)
 2 10 (10.5%) 9 (12.7%) 1 (4.2%)
 3a + 3b 29 (30.5%) 19 (20.0%) 10 (41.7%)
 4a + 4b 12 (12.6%) 6 (6.3%) 6 (25.0%)
 5 4 (4.2%) 3 (4.2%) 1 (4.2%)
CCI (median, [IQR]) 20.9 [0-43.2] 20.9 [0-27.9] 38.6 [19.1-55.6] 0.0065
 Surgical complications 48 (50.5%) 30 (42.3%) 18 (75.0%) 0.0055
 Anastomotic leakage 27 (28.4%) 15 (21.1%) 12 (50.0%) 0.0067
  Anastomotic technique 0.6885
  Linear stapling 18 (18.9%) 10 (14.1%) 8 (33.3%)
 Circular stapling 9 (9.5%) 5 (7.0%) 4 (16.7%)
 Medical complications 31 (41.7%) 21 (29.6%) 10 (41.7%) 0.3181
 Cardiac complications 16 (16.8%) 10 (14.1%) 6 (25.0%) 0.2228
 Pulmonary complications 22 (23.2%) 15 (21.1%) 7 (29.2%) 0.4157

RAMIE, robot-assisted minimally invasive esophagectomy; MIE, minimally invasive esophagectomy; SD, standard deviation; IQR, interquartile range; ICU, intensive care unit; CCI, comprehensive complication index; p<0.05 are marked in bold.