Fig. 3.

Changes in cellularity following standard rotator cuff repair or patch-augmented rotator cuff repair. (A) Schematic showing the biopsy sample site (Core biopsy needle, dotted line) at 4-week post-surgical repair. (B) Representative hematoxylin and eosin (H&E) histological staining showed cellularity changes following patch augmentation or standard repair (no patch; control) group. H&E staining was performed on (a) control, (b) GraftJacket™, and (c) Permacol™ groups, with patch augmentation showing increased disruption of the tendon extracellular matrix. (C) Histological quantification showed lower cellularity per field of view for patch-augmented repair (GraftJacket™ and Permacol™) relative to standard repair control. ∗ denotes a patient who received Permacol™ and exhibited a grossly different tissue response. Copyright obtained from Taylor & Francis and adapted from Mustafa S Rashid et al., 2020.