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. 2022 Mar 1;3:836705. doi: 10.3389/fpain.2022.836705

Table 1.

Characteristic of infants who underwent assessment at 5-years of age.

Characteristic n = 84
Gestational Age, weeksa 27 ± 2
Birth weight, ga 933 ± 256
Growth restriction for weight at birth 7 (8.3%)
Growth restriction for occipito frontal circumference at birth 12 (14.3%)
Male sex 42 (50%)
Antenatal steroids 67 (79.8%)
5-min APGAR scorea 6.2 ± 2.0
Clinical Risk Index for Babies scorea 4.1 ± 3.6
Ventilator daysb 3 (1–18)
Total parenteral nutrition daysb 17 (11–32)
Patent ductus arteriosus requiring treatment 39 (46.4%)
Necrotizing enterocolitis 6 (7.1%)
Retinopathy of prematurity 5 (6%)
Chronic lung disease 28 (33.3%)
Intraventricular hemorrhage on cranial ultrasound 33 (39.3%)
    Grade I 6 (7.1)
    Grade II 18 (21.4)
    Grade III 2 (2.4%)
    Grade IV 7 (8.3%)
Periventricular leukomalacia on cranial ultrasound 6 (7.1%)
Cerebellar hemorrhage on magnetic resonance imaging 17 (20.2%)
    Grade I 8 (9.5%)
    Grade II 4 (4.8%)
    Grade III 3 (3.6%)
    Grade IV 2 (2.4%)
Anesthesia exposure 18 (21.4%)
Inotrope exposure 19 (22.6%)
Fentanyl exposure 62 (73.8%)
Morphine exposure 12 (14.3%)
Midazolam exposure 15 (17.9%)
Dexamethasone exposure 8 (9.5%)
Hydrocortisone exposure 15 (17.9%)
Social risk compositeb 1.5 (0-3)
Income to need ratiob 1.2 (0.8-2.4)
McMaster Family Assessment Deviceb 1.4 (1.1-1.8)
a

Mean ± standard deviation;

b

Median (interquartile range).