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. 2022 Aug 17;13:969660. doi: 10.3389/fimmu.2022.969660

Table 2.

Toxicities after CAR-T therapy in all patients.

Toxicities n (%)
Cytokine-release syndrome grade
0 8(24.2)
1-2 18(54.5)
3-5 7(21.2)
Immune effect or cell associated neurotoxic syndrome 3(9.0)
Hematological toxicity
Neutropenia (III/IV) 33(100)
Anemia (III/IV) 23(69.7)
Thrombocytopenia (III/IV) 30(90.9)
Hemagglutination abnormalities(III/IV) 12(36.4)
Non-neurological and non-hematological toxicity
Pyrexia 26(78.8)
Hypoxia 12(36.4)
Hypotension 1(3.0)
Cardiac failure 2(6.0)
Acute kidney injury 5(15.2)
Ascites/Hydrothorax 0(0)
Pneumonia 4(12.1)
Increase of alanine-aminotransferase 8(24.2)
Increase of Hyperbilirubinemia 1(3.0)
Tumor lysis syndrome 0(0.0)