Table 2.
Toxicities after CAR-T therapy in all patients.
Toxicities | n (%) | |
---|---|---|
Cytokine-release syndrome grade | ||
0 | 8(24.2) | |
1-2 | 18(54.5) | |
3-5 | 7(21.2) | |
Immune effect or cell associated neurotoxic syndrome | 3(9.0) | |
Hematological toxicity | ||
Neutropenia (III/IV) | 33(100) | |
Anemia (III/IV) | 23(69.7) | |
Thrombocytopenia (III/IV) | 30(90.9) | |
Hemagglutination abnormalities(III/IV) | 12(36.4) | |
Non-neurological and non-hematological toxicity | ||
Pyrexia | 26(78.8) | |
Hypoxia | 12(36.4) | |
Hypotension | 1(3.0) | |
Cardiac failure | 2(6.0) | |
Acute kidney injury | 5(15.2) | |
Ascites/Hydrothorax | 0(0) | |
Pneumonia | 4(12.1) | |
Increase of alanine-aminotransferase | 8(24.2) | |
Increase of Hyperbilirubinemia | 1(3.0) | |
Tumor lysis syndrome | 0(0.0) |