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. Author manuscript; available in PMC: 2023 Jan 5.
Published in final edited form as: J Am Soc Mass Spectrom. 2021 Dec 23;33(1):181–188. doi: 10.1021/jasms.1c00318

Figure 2.

Figure 2.

(A) SARS-CoV-2 is a coronavirus named for the transmembrane spike protein on the surface of the infectious virus particle. (B) The spike protein is a trimer consisting of a transmembrane domain, an S2 domain, and an S1 domain which binds to the human receptor ACE2 to initiate the infection of human cells. (C) Recombinant S1 protein monomer containing a histidine tag was immobilized on magnetic beads for use as the target for MagMASS.