TABLE 2.

Antibacterial effect of brucine against three clinical strains of H. pylori using the disk diffusion method.

Sample	Zone of inhibition (mm)
	0.5 µg/disk	1 µg/disk	2 µg/disk	4 µg/disk	8 µg/disk	16 µg/disk	32 µg/disk	MIC50 (µg/ml)
Strain J63 (cagA-)
Brucine	1 ± 0	1.33 ± 0.33	2 ± 0.57	4 ± act0.57	8 ± 0.57	10.66 ± 0.33	14 ± 0.57	16
Metronidazole	3.66 ± 0.33	4.66 ± 0.33	5.33 ± 0.66	7 ± 0.57	10.33 ± 1.20	14.66 ± 0.88	22 ± 1.15	4
Strain J196 (cagA-)
Brucine	1.33 ± 0.33	1.66 ± 0.66	2 ± 0.57	4.66 ± 0.33	7.33 ± 0.33	10 ± 0.57	13 ± 0.57	18
Metronidazole	4 ± 0.57	5 ± 0.57	5 ± 0.57	7.33 ± 0.88	10.3 ± 1.20	15 ± 1.00	20.6 ± 1.33	6
Strain J107 (cagA+)
Brucine	1.66 ± 0.33	2 ± 0.57	2.33 ± 0.33	4.33 ± 0.88	8.66 ± 0.33	11.66 ± 0.88	14 ± 0.57	16
Metronidazole	4 ± 0.57	4.66 ± 0.33	5.66 ± 0.88	8 ± 1.15	11.33 ± 0.66	15.6 ± 0.33	22.6 ± 0.66	4