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. 2022 Aug 17;13:886433. doi: 10.3389/fphar.2022.886433

TABLE 3.

Protective effect of brucine and omeprazole against ethanol-induced gastric ulcer in rats.

Treatment (mg/kg) Ulcer index (UI) % Inhibition
Saline (10 ml/kg) 0 ± 0 _
Ethanol (1 mL/100 g) 10 ± 0.00### 0
Brucine (1 mg/kg) + ethanol (1 mL/100 g) 2 ± 0.93∗∗∗ 80
Brucine (3 mg/kg) + ethanol (1 mL/100 g) 2 ± 0.31∗∗∗ 80
Omeprazole (20 mg/kg) + ethanol (1 mL/100 g) 1 ± 0.13∗∗∗ 90

### p < 0.001 compared to the control saline group; ∗∗∗ p < 0.001 vs. the ethanol group. One-way analysis of variance followed by post hoc Tukey’s test, ± SEM (n = 5).