FIG 1.
Postvaccination serum neutralizing levels vary by prior infection. (A to D) Neutralization titers (PRNT50) for each serum sample are shown by blood sample collection date (92 participants, 260 samples total) (A, B) or by days post-first vaccine dose (68 participants, 226 samples total) (C, D). (B, D) Serum sample data are labeled based on participants’ prevaccination immune status. (B) Pink, seropositive, 23 participants, 86 samples; orange, seronegative, 38 participants, 127 samples; purple, unknown immune status, 31 participants, 47 samples. (D) Pink, seropositive, 16 participants, 70 samples; orange, seronegative, 32 participants, 121 samples; purple, unknown immune status, 20 participants, 35 samples. Dashed lines represent the limit of detection (PRNT50 = 20). Samples without neutralization detected are plotted at half the limit of detection (PRNT50 = 10).