Table 1.
Coding, indications, and composition of the used AIT products and vaccines.
| Code name | Product name | Vendor | Indication | Contained Antigen(s) | Adjuvant |
|---|---|---|---|---|---|
| AIT product 1 | Pollinex® Quattro BEH | Bencard, Allergy | Allergy treatment | 300, 800, or 2000 standardized units (SU)/ml tree pollen allergoids (birch, elder, hazel) adsorbed to L-Tyrosine | 50 µg MPLA per 1.5 ml syringe |
| AIT product 2 | ALLERGOVIT® BEH | Allergopharma | Allergy treatment | 10000 therapeutic units (TE)/ml tree pollen allergoids (35% birch, 30% elder, 35% hazel) | Aluminum hydroxide |
| AIT product 3 | Purethal® Spring trees I | HAL Allergy | Allergy treatment | 20000 arbitrary units (AUM)/ml tree pollen allergoids (33% birch, 33% elder, 33% hazel) | 0.55 mg aluminum hydroxide per 3 ml solution |
| AIT product 4 | Allergovit® birch | Allergopharma | Allergy treatment | 10000 TE/ml birch pollen allergoids | Aluminum hydroxide |
| AIT product 5 | Purethal® birch | HAL Allergy | Allergy treatment | 20000 AUM/ml birch pollen allergoids | 0.55 mg aluminum hydroxide per 3 ml solution |
| Vaccine 1 | Fendrix® | GlaxoSmithKline | Prevention of hepatitis B infection | 20 µg Hepatitis B surface antigen per 0.5 ml syringe | AS04 (50 µg MPLA & adsorbed to 0.5 mg aluminum phosphate per 0.5 ml syringe) |
| Vaccine 2 | Cervarix® | GlaxoSmithKline | Prevention of cervical cancer | 40 µg recombinant human papilloma virus L1 proteins per 0.5 ml syringe | AS04 (50 µg MPLA & adsorbed to 0.5 mg aluminum phosphate per 0.5 ml syringe) |
BEH, birch; elder, hazel; SU, standardized units; TE, therapeutic units; AUM, arbitrary units; MPLA, monophosphoryl lipid A; AS, adjuvant system.