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. 2022 Aug 1;10(4):e02484-21. doi: 10.1128/spectrum.02484-21

FIG 1.

FIG 1

Replication of C. burnetii NMII in murine bone marrow-derived macrophages (BMDM). (A and B) Growth curves of C. burnetii NMII in Vero cells and C57BL/6 BMDM over 7 days (A) or RAW 264.7 (RAW) cells and BMDM over 4 days (B). Each point is the mean of results from 3 independent experiments, with error bars representing standard deviations. (C and D) Confocal micrographs of C. burnetii NMII wild-type-infected (C) or dotA::Tn mutant-infected (D) BMDM at 4 days postinfection. Coxiella was stained green, LAMP-1 is shown in red, and DNA is stained blue with DAPI. Scale bar, 10 μm.