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. 2022 Jul 12;10(4):e00118-22. doi: 10.1128/spectrum.00118-22

TABLE 1.

Drug susceptibilities of 69 Mycobacterium abscessus complex isolates

Antimicrobial agent No. (%) of isolates with drug susceptibility
MIC (μg/mL)
Sa Ia Ra S I R
Imipenemb 3 (4.41) 65 (95.59) ≤4 8–16 ≥32
Linezolidb 5 (7.35) 2 (2.94) 61 (89.71) ≤8 16 ≥32
SXTb 1 (1.47) 67 (98.53) ≤2/38 ≥4/76
Cefoxitinb 3 (4.41) 34 (50.00) 31 (45.59) ≤16 32–64 ≥128
Tobramycinb 6 (8.82) 62 (91.18) ≤2 4 ≥8
Doxycyclineb 3 (4.41) 3 (4.41) 62 (91.18) ≤1 2–4 ≥8
Amikacinb 44 (64.71) 22 (32.35) 2 (2.94) ≤16 32 ≥64
Ciprofloxacinb 2 (2.94) 66 (97.06) ≤1 2 ≥4
Moxifloxacinb 1 (1.47) 67 (98.53) ≤1 2 ≥4
Clarithromycinb 13 (19.12) 55 (80.88) ≤2 4 ≥8
AMCc 68 (100) ≤16 32 ≥64
Cefepimec 68 (100) ≤8 16 ≥32
Ceftriaxonec 1 (1.47) 67 (98.53) ≤16 32 ≥64
Minocyclinec 1 (1.47) 3 (4.41) 64 (94.12) ≤1 2–4 ≥8
Tigecyclinec 67 (98.53) 1 (1.47) ≤4 >4
a

S, susceptible; I, intermediate; R, resistant.

b

First-line antimicrobials against MABC isolates.

c

Secondary antimicrobials against MABC isolates. Previously reported interpretation criteria are used in this study (49).