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. 2022 Aug 31;378:e070688. doi: 10.1136/bmj-2022-070688

Table 2.

Baseline characteristics of participants from Moli-sani Study cohort (n=22 895) across quarters of ultra-processed food intake (weight ratio). Values are numbers (percentages) unless stated otherwise

Characteristics Quarters of ultra-processed food intake P value*
1 (n=5723) 2 (n=5724) 3 (n=5724) 4 (n=5724)
Mean (IQR) FSAm-NPS dietary index 6.7 (6.0 to 7.8) 7.3 (6.7 to 8.2) 7.7 (7.1 to 8.5) 8.0 (7.3 to 8.8) -
Mean (IQR) ultra-processed food intake, weight ratio 4.1 (3.2 to 5.3) 7.7 (6.8 to 8.5) 11.5 (10.3 to 12.6) 19.9 (15.6 to 22.0) -
Mean (SD) age, years 61.5 (10.7) 56.9 (11.3) 53.2 (10.9) 50.1 (10.8) <0.001
Male sex 3347 (58.5) 2798 (48.9) 2488 (43.5) 2289 (40.0) <0.001
Educational level: <0.001
 Up to lower secondary 3664 (64.0) 3141 (54.9) 2706 (47.3) 2441(42.6)
 Upper secondary 1529 (26.7) 1845 (32.2) 2212 (38.6) 2389 (41.7)
 Postsecondary 527 (9.2) 727 (12.7) 805 (14.1) 890 (15.5)
 Missing data 3 (0.1) 11 (0.2) 1 (<0.1) 4 (0.1)
Housing: 0.04
 Rent 411 (7.2) 460 (8.0) 519 (9.1) 620 (10.8)
 1 dwelling ownership 4790 (83.7) 4731 (82.7) 4678 (81.7) 4618 (80.7)
 >1 dwelling ownership 510 (8.9) 518 (9.0) 517 (9.0) 481 (8.4)
 Missing data 12 (0.2) 15 (0.3) 10 (0.2) 5 (0.1)
Urban residence 3722 (65.0) 3787 (66.2) 3918 (68.4) 3953 (69.1) <0.001
Smoking status: 0.003
 Non-smoker 2583 (45.1) 2842 (49.7) 2912 (50.9) 3020 (52.8)
 Current smoker 1198 (20.9) 1240 (21.7) 1338 (23.4) 1483 (25.9)
 Former smoker 1938 (33.9) 1638 (28.6) 1470 (25.7) 1217 (21.3)
 Missing data 4 (0.1) 4 (0.1) 4 (0.1) 4 (0.1)
Mean (SD) leisure time physical activity, MET-h/day 3.8 (4.5) 3.6 (4.0) 3.5 (3.6) 3.4 (3.8) <0.001
Mean (SD) body mass index 28.2 (4.6) 28.2 (4.7) 27.9 (4.7) 27.6 (4.9) <0.001
Cardiovascular disease: 0.3
 No 5145 (89.9) 5316 (92.9) 5429 (94.8) 5457 (95.3)
 Yes 463 (8.1) 322 (5.6) 210 (3.7) 192 (3.4)
 Missing data 115 (2.0) 86 (1.5) 85 (1.5) 75 (1.3)
Cancer: 0.3
 No 5455 (95.3) 5508 (96.2) 5513 (96.3) 5541 (96.8)
 Yes 239 (4.2) 190 (3.3) 201 (3.5) 164 (2.9)
 Missing data 29 (0.5) 26 (0.5) 10 (0.2) 19 (0.3)
Diabetes: <0.001
 No 5119 (89.4) 5351 (93.5) 5485 (95.8) 5562 (97.2)
 Yes 516 (9.0) 308 (5.4) 170 (3.0) 101 (1.8)
 Missing data 88 (1.5) 65 (1.1) 69 (1.2) 61 (1.1)
Hypertension: 0.08
 No 3458 (60.4) 3896 (68.1) 4286 (74.9) 4620 (80.7)
 Yes 2208 (38.6) 1794 (31.3) 1405 (24.5) 1067 (18.6)
 Missing data 57 (1.0) 34 (0.6) 33 (0.6) 37 (0.7)
Hyperlipidaemia: <0.001
 No 4970 (86.8) 5163 (90.2) 5369 (93.8) 5427 (94.8)
 Yes 683 (11.9) 497 (8.7) 317 (5.5) 262 (4.6)
 Missing data 70 (1.2) 64 (1.1) 38 (0.7) 35 (0.6)

FSAm-NPS=Food Standards Agency nutrient profiling system; IQR=interquartile range; SD=standard deviation

Means were adjusted for age, sex, and energy intake.

*

Obtained using generalised linear models for both continuous and categorical dependent variables adjusted for age, sex, and energy intake.

Data for leisure time physical activity and body mass index were missing for 197 and 13 participants, respectively.