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. 2022 Jun 14;10(4):e02741-21. doi: 10.1128/spectrum.02741-21

TABLE 3.

Duration of Cryptosporidium shedding compared between groups

Characteristic Reference level Odds ratio of no longer shedding, at any given time point (parametric model)
Test of difference (nonparametric model)b
95% CI for ORa
OR From To P value Window of significantly different shedding quantityc
Age 0–11 mo Age 12–59 mo 1.07 0.76 1.50 0.32 22 to 52 days (higher)
Male Female 1.15 0.83 1.59 0.12 36 to 69 days (higher)
Acute malnutrition (MAM or SAM) No acute malnutrition (NAM) 0.97 0.68 1.38 0.70 No window of significant difference
Any dehydration No dehydration 0.75 0.55 1.01 0.03 32 to 40 days (lower)
C. parvum C. hominis 0.94 0.57 1.55 0.31 43 to 69 days (higher)
C. hominis gp60 allele family Id C. hominis gp60 allele family other than Id 1.51 1.01 2.23 0.04 11 to 55 days (higher)
a

OR, odds ratios obtained from accelerated failure time log-logistic models, adjusted for sex and age (in months); age adjusted for sex only; sex adjusted for age only.

b

Generalized log-rank test using within-subject resampling (not adjusted for sex and age).

c

Window of significantly different shedding quantity (Cryptosporidium DNA copies/g, by qPCR) in days after onset of diarrhea; estimates obtained from generalized additive mixed model difference smooths, adjusted for sex and age (in months); age adjusted for sex only; sex adjusted for age only.