Differential species of gut microbiota between the CON, T2DM, and DN groups. (A) Annotated branch diagram of the different species of the gut microbiota in CON, T2DM, and DN patients. (B) LEfSe analysis showing the most differentially abundant taxa between the CON, T2DM, and DN groups. Red, blue, and green bars represented species with relatively higher abundance in CON, T2DM, and DN patients, respectively. Only species with an LDA of >2 are shown. (C) Increased or decreased strains in the CON, T2DM, and DN groups. *, P < 0.05, compared with CON group; #, P < 0.05, compared with T2DM group.