TABLE 3.
Cohen’s kappa statistic measure of agreement between different cryptococcal antigen testing methodsa
Sample | Cohen’s kappa | Expected agreement | Observed agreement | SE | P value |
---|---|---|---|---|---|
Urine vs sCrAg | 0.32 | 73.7% | 82.0% | 0.025 | <0.0001 |
FP whole blood vs sCrAg | 0.60 | 86.2% | 94.5% | 0.026 | <0.0001 |
CSF vs urine | 0.181 | 41.75% | 52.30% | 0.071 | 0.023 |
CSF vs FP whole blood | 0.373 | 53.40% | 70.77% | 0.1 | <0.0001 |
sCrAg, serum cryptococcal antigen laboratory-based testing; FP, fingerprick; CSF, cerebrospinal fluid.