TABLE 5.
Variant | CT value | Sensitivity (95% CI) (%) of test |
|||||||
---|---|---|---|---|---|---|---|---|---|
AAZ | AMP | Novel | Biospeedia | R-Biopharm | Siemens | Abbott | Biosynex | ||
Alpha | ≤20 | 100 (89.1–100) | 96.9 (83.8–99.9) | 100 (88.8–100) | 96.8 (83.3–99.9) | 100 (88.1–100) | 100 (89.1–100) | 100 (89.1–100) | 100 (89.1–100) |
21–25 | 87.5 (61.7–98.4) | 93.8 (69.8–99.8) | 86.7 (59.5–98.3) | 93.3 (68.1–99.8) | 73.3 (44.9–92.2) | 87.5 (61.7–98.4) | 60.0 (32.3–83.7) | 87.5 (61.7–98.4) | |
26–30 | 50.0 (6.8–93.2) | 75.0 (19.4–99.4) | 25.0 (0.6–80.6) | 50.0 (6.8–93.2) | 50.0 (6.8–93.2) | 50.0 (6.8–93.2) | 0 (0–60.2) | 25.0 (0.6–80.6) | |
>30 | 0 (0–84.2) | 0 (0–84.2) | 0 (0–84.2) | 0 (0–84.2) | 50.0 (1.3–98.7) | 0 (0–84.2) | 0 (0–84.2) | 0 (0–84.2) | |
≤25 | 95.8 (85.7–99.5) | 95.8 (85.7–99.5) | 95.7 (85.2–99.5) | 95.7 (85.2–99.5) | 90.9 (78.3–97.5) | 95.8 (85.7–99.5) | 87.2 (74.3–95.2) | 95.8 (85.7–99.5) | |
≤30 | 92.3 (81.5–97.9) | 94.2 (84.1–98.8) | 90.0 (78.2–96.7) | 92.0 (80.8–97.8) | 87.5 (74.8–95.3) | 92.3 (81.5–97.9) | 80.4 (66.9–90.2) | 90.4 (79.0–96.8) | |
Any | 88.9 (77.4–95.8) | 90.7 (79.7–96.9) | 86.5 (74.2–94.4) | 88.5 (76.6–95.6) | 86.0 (73.3–94.2) | 88.9 (77.4–95.8) | 77.4 (63.8–87.7) | 87.0 (75.1–94.6) | |
Beta | ≤ 20 | 100 (29.2–100) | 100 (29.2–100) | 100 (29.2–100) | 100 (29.2–100) | 100 (29.2–100) | 100 (29.2–100) | 66.7 (9.4–99.2) | 100 (29.2–100) |
21–25 | 100 (73.5–100) | 100 (73.5–100) | 100 (73.5–100) | 100 (73.5–100) | 100 (73.5–100) | 100 (73.5–100) | 91.7 (61.5–99.8) | 100 (73.5–100) | |
26–30 | 66.7 (22.3–95.7) | 83.3 (35.9–99.6) | 66.7 (22.3–95.7) | 83.3 (35.9–99.6) | 66.7 (22.3–95.7) | 66.7 (22.3–95.7) | 66.7 (22.3–95.7) | 50.0 (11.8–88.2) | |
>30 | |||||||||
≤25 | 100 (78.2–100) | 100 (78.2–100) | 100 (78.2–100) | 100 (78.2–100) | 100 (78.2–100) | 100 (78.2–100) | 86.7 (59.5–98.3) | 100 (78.2–100) | |
≤30 | 90.5 (69.6–98.8) | 95.2 (76.2–99.9) | 90.5 (69.6–98.8) | 95.2 (76.2–99.9) | 90.5 (69.6–98.8) | 90.5 (69.6–98.8) | 81.0 (58.1–94.6) | 85.7 (63.7–97.0) | |
Any | 88.9 (77.4–95.8) | 90.7 (79.7–96.9) | 86.5 (74.2–94.4) | 88.5 (76.6–95.6) | 86.0 (73.3–94.2) | 88.9 (77.4–95.4) | 77.4 (63.8–87.7) | 87.0 (75.1–94.6) | |
Delta | ≤20 | 97.1 (84.7–99.9) | 100 (89.7–100) | 100 (89.7–100) | 100 (89.7–100) | 94.1 (80.3–99.3) | 100 (89.7–100) | 94.1 (80.3–99.3) | 97.1 (84.7–99.9) |
21–25 | 84.6 (54.6–98.1) | 100 (75.3–100) | 92.3 (64.0–99.8) | 100 (75.3–100) | 61.5 (31.6–86.1) | 84.6 (54.6–98.1) | 69.2 (38.6–0.9) | 92.3 (64.0–99.8) | |
26–30 | 0 (0–41) | 42.9 (9.9–81.6) | 14.3 (0.4–57.9) | 14.3 (0.4–57.9) | 28.6 (3.7–71.0) | 14.3 (0.4–57.9) | 0 (0–41.0) | 0 (0–41.0) | |
>30 | |||||||||
≤25 | 93.6 (82.5–98.7) | 100 (92.5–100) | 97.9 (88.7–99.9) | 100 (92.5–100) | 85.1 (71.7–93.8) | 95.7 (85.5–99.5) | 87.2 (74.3–95.2) | 95.7 (85.5–99.5) | |
≤30 | 81.5 (68.6–90.7) | 92.6 (82.1–97.9) | 87.0 (75.1–94.6) | 88.9 (77.4–95.8) | 77.8 (64.4–88.0) | 85.2 (72.9–93.4) | 75.9 (62.4–86.5) | 83.3 (70.7–92.1) | |
Any | 88.9 (77.4–95.8) | 90.7 (79.7–96.9) | 86.5 (74.2–94.4) | 88.5 (76.6–95.6) | 86.0 (73.3–94.2) | 88.9 (77.4–95.8) | 77.4 (63.8–97.7) | 87.0 (75.1–94.6) | |
Omicron (BA.1) | ≤20 | 100 (71.5–100) | 100 (71.5–100) | 100 (71.5–100) | 100 (71.5–100) | 100 (71.5–100) | 100 (71.5–100) | 90.9 (58.7–99.8) | 90.9 (58.7–99.8) |
21–25 | 100 (76.8–100) | 100 (76.8–100) | 100 (76.8–100) | 100 (76.8–100) | 85.7 (57.2–98.2) | 100 (76.8–100) | 92.9 (66.1–99.8) | 92.9 (66.1–99.8) | |
26–30 | 69.2 (38.6–90.9) | 76.9 (46.2–95.0) | 69.2 (38.6–90.9) | 69.2 (38.6–90.9) | 38.5 (13.9–68.4) | 61.5 (31.6–86.1) | 30.8 (9.1–61.4) | 38.5 (13.9–68.4) | |
>30 | 8.3 (0.2–38.5) | 8.3 (0.2–38.5) | 8.3 (0.2–38.5) | 8.3 (0.2–38.5) | 8.3 (13.9–68.4) | 8.3 (0.2–38.5) | 8.3 (0.2–38.5) | 8.3 (0.2–38.5) | |
≤25 | 100 (86.3–100) | 100 (86.3–100) | 100 (86.3–100) | 100 (86.3–100) | 92.0 (74.0–99.0) | 100 (86.3–100) | 92.0 (74.0–99.0) | 92.0 (74.0–99.0) | |
≤30 | 89.5 (75.2–97.1) | 92.1 (78.6–98.3) | 89.5 (75.2–97.1) | 89.5 (75.2–97.1) | 73.7 (56.9–86.6) | 86.8 (71.9–95.6) | 71.1 (54.1–84.6) | 73.7 (56.9–86.6) | |
Any | 70.0 (55.4–82.1) | 70.0 (55.4–82.1) | 70.0 (55.4–82.1) | 70.0 (55.4–82.1) | 58.0 (43.2–71.8) | 68.0 (53.3–80.5) | 56 (41.3–70.0) | 58.0 (43.2–71.8) |