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. 2022 Jul 28;10(4):e00641-22. doi: 10.1128/spectrum.00641-22

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Copyright © 2022 Liu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 2 — Treatment effect of B. coagulans, COSs, and synbiotic on DSS-induced colitis mice. (A) body weight change, (B) disease activity index (DAI), (C) macroscopic images of the colons, (D) colons length, (E) spleen weight/body weight ratio. Data are shown as means ± SEM (n = 10 per group). Data with different superscript letters (a, b and c) are significantly different (P < 0.05) according to two-way ANOVA (A and B) and one-way ANOVA (D and E) followed by Tukey’s test. Ctrl: healthy control; DSS: DSS-treated group; B. co, COSs, and Synbiotic: supplementation of B. coagulans spores, COSs, or spores + COSs, respectively.