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. 2022 Jul 28;10(4):e00641-22. doi: 10.1128/spectrum.00641-22

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Copyright © 2022 Liu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 5 — B. coagulans, COSs and synbiotic regulated the composition of gut microbiota. (A-C) Alpha-diversity indices. (D) Principal-component analysis of Bray-Curtis distance (the difference in PC1 and PC2 was 21.8% and 14.4%). (E and F) The relative abundance of fecal bacterial phylum (E), and family (F). (G) Analysis of differences in the microbial taxa by LEfSe in different groups. (H) The relative abundance of B. coagulans. Concentrations of fecal acetate (I), propionate (J), and butyrate (K). Ctrl: healthy control; DSS: DSS-treated group; B. co, COSs and Synbiotic: supplementation of B. coagulans spores, COSs or spores + COSs, respectively.