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. 2022 Jul 28;10(4):e00641-22. doi: 10.1128/spectrum.00641-22

FIG 6.

FIG 6

Effect of B. coagulans, COSs, and synbiotic on the expression of tight junction proteins. (A) Microscopic images of proximal colonic tissues stained with immunohistochemical of Occludin, Claudin, Zo-1, Muc2. Scale bars represent 100 μm. Arrows indicate the IHC positivity. (B) Mean optical densities with Image-pro plus soft of respective group is illustrated in the graph. Data are shown as means ± SEM. Data with different superscript letters are significantly different (P < 0.05) according to one-way ANOVA followed by Tukey’s test. Ctrl: healthy control; DSS: DSS-treated group; B. co, COSs, and Synbiotic: supplementation of B. coagulans spores, COSs, or spores + COSs, respectively.